Generic Doxycycline is used to treat bacterial infections, including pneumonia and other respiratory tract infections; lyme disease; acne; infections of skin, gum disease, genital, and urinary systems; anthrax (after inhalational exposure) and other bacterial infections such as gonorrhea and chlamydia.
Generic Doxycycline is also used to prevent malaria and can also be used to prevent it when visiting high-risk malarial areas, in particular areas where the malaria parasite is resistant to chloroquine.
Working Mechanism of Doxycycline
Generic Doxycycline works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. Doxycycline therefore stops the spread of the infection and the remaining bacteria eventually die.
Missed Dose of Doxycycline
Take the missed dose of Doxycycline as soon as you remember. However, if it is almost time for the next dose of Doxycycline, skip the missed dose and take only the next regularly scheduled dose of Doxycycline. Do not take a double dose of Doxycycline.
Excess Dose of Doxycycline
Conditions for Storage of Generic Doxycycline
Store Generic Doxycycline at room temperature away from moisture and heat.
Potencies of Doxycycline
Food and Drug interactions with Doxycycline
- The absorption of doxycycline from the gut may be reduced by the following:
- In addition, Generic doxycycline reduces the absorption of iron preparations taken by mouth.
- Dose of Doxycycline may reduce the effectiveness of the combined oral contraceptive pill.
- Doxycycline may increase the anti-blood-clotting effects of anticoagulants such as warfarin. People taking this type of medicine should be monitored when Generic doxycycline is first added to treatment.
- The following medicines may reduce the blood level of doxycycline:
- barbiturates, e.g. phenobarbitone
- Your doctor may need to increase the dose of doxycycline if you are taking these medicines.
- Tetracyclines in general may decrease the effectiveness of penicillin type antibiotics. Doxycycline should be avoided with penicillin.
- Alcoholics may have reduced blood levels of doxycycline. This is because in this group of people alcohol stimulates the liver to metabolize the Generic doxycycline. Alcohol has not been found to have this effect in people who drink moderately.
Contraindications with Doxycycline
Generic Doxycycline is contraindicated in the following:
- Allergy to other tetracycline antibiotics, e.g. doxycycline, minocycline
- Children under 12 years of age
- Allergy to one or any of its ingredients
Precautions with Doxycycline
Generic Doxycycline should be used with caution in:
- Decreased liver function
- Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias)
- Long-term inflammation of skin and some internal organs (systemic lupus erythematosus)
- People taking any medicines with potential to cause adverse effects on the liver
- Blood disorders
- Abnormal reaction of the skin to light, usually a rash (photosensitivity)
- Loss of appetite
- Disturbances of liver function
- Inflammation of the food pipe (oesophagitis)
- Difficulty or pain when swallowing (dysphagia)
- Inflammation of the intestines (enterocolitis)
- Mild increase in pressure within the skull (benign intracranial hypertension)
- Hypersensitivity reactions such as swelling of the lips, throat and tongue (angioedema), itchy blistering rash or anaphylactic shock
- Nausea and vomiting
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Generic Cipro is used for the treatment of:
- Infection of the blood (septicaemia or blood poisoning)
- Infection of the organs associated with breathing, including nasal passages, sinuses, windpipe and lungs (respiratory tract)
- Infections of the stomach and intestines
- Infections of the urinary tract
- Prevention of infection (usually after surgery)
- Prevention of meningococcal meningitis
- Treatment of chest infections in children 5 years and over who have cystic fibrosis or infections in children where the benefit exceeds the risk
Working Mechanism of Cipro
Generic Cipro works by entering the bacterial cell and inhibiting a chemical called DNA-gyrase, which is involved in the production of genetic material (DNA). This therefore prevents the bacteria from reproducing and their growth is stopped.
Missed Dose of Cipro
Take the missed dose of Cipro as soon as you remember. However, if it is almost time for the next dose of Cipro, skip the missed dose and take only the next regularly scheduled dose of Cipro. Do not take a double dose of Cipro.
Excess Dose of Cipro
Conditions for Storage of Generic Cipro
Store Generic Cipro at room temperature away from moisture and heat.
Potencies of Generic Cipro
Food and Drug interactions with Cipro
- When used with Generic Cipro the following medications increase the risk of convulsions:
- Non-steriodal anti-inflammatory drugs (NSAID’s)
- Theophylline (ciprofloxacin also increases the concentration of theophylline in the blood – monitor theophylline levels)
- The blood thinning effects of warfarin and nicoumalone are enhanced with Cipro.
- Generic Cipro increases the risk of kidney damage when used with cyclosporin.
- The manufacturer advises that opioid analgesics be avoided when using Generic Cipro, as it decreases the levels of Generic Cipro in the blood.
- Sucralfate reduces the absorption of Cipro – do not take within four hours of taking Generic Cipro.
Contraindications with Cipro
Generic Cipro is contraindicated in the following:
- Not generally recommended in children and growing adolescents except for chest infection attacks in cystic fibrosis patients or where benefit exceeds risk
- Generic Cipro should not be used if you are allergic to one or any of its ingredients.
- Generic Cipro is not approved for use by children younger than 18 years of age (except for use in post-exposure inhalational anthrax). It may interfere with bone development.
- Pregnancy & Breast-feeding
Precautions with Cipro
Generic Cipro should be used with caution in:
- Decreased kidney function
- History of convulsions, e.g. epilepsy
- History of disorders of the Central Nervous System (CNS)
- Lack of the enzyme G6PD in the blood (G6PD deficiency)
- Urine less acidic (alkalosis)