Urecholine and its Uses
Generic Urecholine treats urinary or bladder problems caused by surgery, drugs, or other factors. Urecholine stimulates the bladder & helps empty the bladder and increases urination.
Working Mechanism of Urecholine
Generic Urecholine chloride mimics the action of acetylcholine, which is a chemical found naturally in the body. Acetylcholine stimulates receptors, called muscarinic receptors, which leads to a range of different effects.
Muscarinic receptors are found all over the body, including the muscle which surrounds the bladder and the muscles of the gastro-intestinal tract. Stimulation of the bladder muscle receptors enables the bladder to empty while stimulation of the oesophageal (gullet) muscles prevents the reflux of stomach contents.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of Urecholine.
Excess Dose of Urecholine
Conditions for Storage of Urecholine
Store Urecholine at room temperature away from moisture and heat.
Potencies of Urecholine
Food and Drug interactions with Urecholine
- When taken with anti-muscarinic medicines (such as ipatropium bromide or atropine sulphate) the effects of Urecholine chloride may be reduced.
- Generic Urecholine may interact with the following medicines:
- donepezil (Aricept);
- tacrine (Cognex);
- quinidine (Cardioquin, others); or
- procainamide (Pronestyl, Procan SR).
Contraindications with Urecholine
Urecholine is contraindicated in the following:
- Blockage of the gut (intestinal obstruction)
- Known sensitivity or allergy to any ingredient
- Obstruction of the urinary tract (urethra)
- People who have recently had a heart attack
- Recent surgical procedure involving the joining together of ends of the intestine after a section has been removed (intestinal anastomosis)
- Pregnancy & Breast-Feeding
Precautions with Urecholine
Generic Urecholine should be used with caution in children & elderly people.
- Blurred vision
- Fluctuating abdominal pain (colic)
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Levaquin and Its Uses
Generic Levaquin is a quinolone antibiotic used in adults to treat lung, sinus, skin, and urinary tract infections caused by certain germs called bacteria. Generic Levaquin kills many of the types of bacteria that can infect the lungs, sinuses, skin, and urinary tract.
Working Mechanism of Levaquin
Generic Levaquin works by entering the bacterial cell and inhibiting a chemical called DNA-gyrase, which is involved in the production of genetic material (DNA). This therefore prevents the bacteria from reproducing and their growth is stopped.
Missed Dose of Levaquin
Take the missed Dose of Levaquin as soon as you remember. However, if it is almost time for the next Dose of Levaquin, skip the missed dose and take only the next regularly scheduled Dose of Levaquin. Do not take a double dose of Levaquin unless otherwise directed by your doctor.
Excess Dose of Levaquin
Generic Levaquin in excess shows the symptom of seizures.
Conditions for storage of Generic Levaquin
Store Generic Levaquin at room temperature away from moisture and heat.
Potencies of Levaquin
Food and Drug Interactions with Levaquin
- If Generic Levaquin is taken with non-steroidal anti-inflammatory drugs there is an increased risk of convulsions.
- Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 2 hours before or 2 hours after a dose of Levaquin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of Levaquin can greatly decrease the effects of the antibiotic.
- Generic Levaquin increases the risk of kidney damage when used with cyclosporin.
Contraindications with Levaquin
Generic Levaquin is contraindicated in:
- Not generally recommended for use in children and growing adolescents.
- if you are allergic to one or any of its ingredients.
Precautions with Levaquin
Generic Levaquin should be used with caution in the following conditions:
- Decreased kidney function
- History of convulsions, e.g. epilepsy
- History of disorders of the Central Nervous System (CNS)
- Lack of the enzyme G6PD in the blood (G6PD deficiency)
- Itching (pruritus)
- Abdominal pain
- Disturbed sleep
- Indigestion (dyspepsia)
- Alteration in results of liver function tests
- Nausea and vomiting
- Loss of appetite
- Weakness or loss of strength (asthenia)
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Erythromycin and its Uses
Generic Erythromycin is an antibiotic used to treat certain infections caused by bacteria, such as bronchitis; diphtheria; Legionnaires’ disease; pertussis (whooping cough); pneumonia; rheumatic fever; venereal disease (VD); and ear, intestine, lung, urinary tract, and skin infections.
Working Mechanism of Erythromycin
Generic Erythromycin works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. Generic Erythromycin therefore stops the spread of infection and remaining bacteria are killed by the body’s immune system or eventually die.
Missed Dose of Erythromycin
Take the missed dose of Erythromycin as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose of Erythromycin and take the next one as directed. Do not take a double dose of Erythromycin unless otherwise directed by your doctor.
Excess Dose of Erythromycin
Conditions for Storage of Erythromycin
Store Erythromycin at room temperature away from moisture and heat.
Potencies of Erythromycin
Food and Drug Interactions with Erythromycin
- Generic Erythromycin must not be taken by people taking any of the following medicines:
- Generic Erythromycin may also increase the blood levels of the following medicines:
- methylprednisolone and possibly other corticosteroids
- midazolam, triazolam and possibly alprazolam
- theophylline (in addition theophylline may decrease the blood level of erythromycin, making it less effective)
If the blood levels of these medicines are raised by Generic erythromycin it may lead to an increase in the effects of these medicines, but also a possible increased risk of their side effects. Combined use should therefore be well monitored.
- Generic Erythromycin may also increase the blood levels and hence anti-blood-clotting effects of the anticoagulants nicoumalone and warfarin. As this may increase the risk of bleeding, people taking these combinations, particularly elderly people, may need more frequent monitoring of their blood clotting time so the dose of anticoagulant can be adjusted if necessary.
- Generic Erythromycin may also increase the blood levels of the cholesterol-lowering medicines, atorvastatin and lovastatin. This may increase the risk of side effects on the muscles (myopathy) from these medicines.
- The following medicines may increase the blood level of erythromycin, thereby increasing the risk of its side effects:
- protease inhibitors such as ritonavir, lopinavir and amprenavir.
- If you are taking a combined oral contraceptive pill there may be a very low risk that Generic Erythromycin may make it less effective at preventing pregnancy. Although the risk of this is very low, the personal and ethical consequences of an unwanted pregnancy can be very serious. For this reason the Family Planning Association recommends that women taking combined oral contraceptives should use an extra method of contraception (e.g. condoms) while taking a short course of Erythromycin, and for seven days after finishing the course. If the seven days run beyond the end of a pill packet, a new packet should be started without a break (in the case of ED pills the inactive tablets should be omitted).
Precautions with Erythromycin
Generic Erythromycin should be used with caution in the following:
- Abnormal heart rhythm seen on the heart monitoring trace (ECG) as a ‘prolonged QT interval’
- Abnormal muscle weakness (myasthenia gravis)
- Decreased kidney function
- Decreased liver function
- Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias)
- Abdominal pain
- Abnormal heart beats (arrhythmias)
- Yellowing of the skin and eyes (jaundice)
- Nausea and vomiting
- Inflammation of the liver (hepatitis)
- Reversible hearing loss (usually only after large doses)
- Disturbances of liver function
- Allergic skin reactions